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Year : 2022  |  Volume : 10  |  Issue : 1  |  Page : 17-19

Effectiveness of resolvins in treating periodontitis: A review

1 Department of Periodontics, Government College of Dentistry, Indore, Madhya Pradesh, India
2 Department of Conservative Dentistry, Government College of Dentistry, Indore, Madhya Pradesh, India
3 Department of Pedodontics and Preventive Dentistry, Hitkarini Dental College, Jabalpur, Madhya Pradesh, India
4 Department of Periodontics, Pacific Dental College and Hospital, Udaipur, Rajasthan, India

Correspondence Address:
Dr. Manish Varma
Department of Periodontics, Government College of Dentistry, Indore, Madhya Pradesh.
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/INJO.INJO_5_22

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Periodontitis is a prevalent condition that affects more than 10% of individuals worldwide. Periodontitis may lead to tooth loss besides a worse quality of life in severe instances. Periodontitis has a complex etiology. In a vulnerable host, a subgingival dental biofilm provokes an inflammatory as well as immunological response, eventually leading to irreparable loss of the periodontium (alveolar bone as well as periodontal ligament). Dental practitioners must grasp the pathogenesis, main etiology, risk factors, contributing variables, together with therapy regimens in order to effectively manage periodontitis. Resolvins enhance inflammation resolution via a variety of ways, including limiting neutrophil penetration and phagocytosing apoptotic neutrophils to remove the lesion, in addition to improving inflammation clearance inside the lesion to endorse tissue regeneration.

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